Bafetinib


Catalog Number Pack Size List Price* Quantity
HY-50868-5MG 5 mg 128,00 Add
HY-50868-1ML 10mM/1mL 158,00 Add
HY-50868-10MG 10 mg 178,00 Add
HY-50868-50MG 50 mg 330,00 Add
HY-50868-100MG 100 mg 584,00 Add
HY-50868-S-1ST Sample   Inquire

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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Bafetinib is an orally active Lyn/Bcr-Abl tyrosine kinase inhibitor. Bafetinib enhances the activity of several pro-apoptotic Bcl-2 homology (BH) 3-pure proteins (Bim, Bad, Bmf, and Bik) through intrinsic apoptotic pathways regulated by the Bcl-2 family, and induces apoptosis of Ph+ leukemia cells. Bafetinib has antitumor activity[1][2][3].

Category Biochemicals
Supplier MedChem Express
Regulatory Status RUO
Research Field Cancer, Apoptosis,Protein Tyrosine Kinase/RTK
Format Solubility: DMSO : 100 mg/mL (ultrasonic)
Grade Clinical information: Phase 2
Purity 99.77%
Molecular Formula C30H31F3N8O
Molecular Weight 576.62
CAS-Number 859212-16-1
Storage Conditions -20°C, 3 years; 4°C, 2 years (Powder)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room Temperature
Material Safety Data Sheet Download PDF