6xHis-UbE2B


Catalog Number Pack Size List Price* Quantity
C1200-25uG 25 µg 353,00 Add
C1201-100uG 100 µg 610,00 Add

* CHF, excl. 8.1% VAT and shipping costs


Product Description

Please inquire a quote for two or more UBPBio products

Ube2B is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It shares 95% amino acid sequence identity with Ube2A. One function of Ube2B involves the formation of Ube2B/ Rad18 (an E3 enzyme) complex to monoubiquitinate proliferating cell nuclear antigen (PCNA) thus activating it to repair DNA damage. The Ube2B/Rad18 complex is recruited to the replication fork of the damaged DNA to start the post-replication repair.

Category Enzyme/Substrate
Supplier UBPBio
Regulatory Status RUO
Species Specificity Hu
Format 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol
Storage Conditions -80°C
Disclaimer Shipped on dry ice - extra freight charge will occur
Tech. Data Sheet View datasheet
Link To Supplier http://www.ubpbio.com
Shipping Details Dry ice
Material Safety Data Sheet Download PDF