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Sample Type

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Anti-HSP60 Monoclonal Antibody (Clone: LK1) - ATTO 594

Catalog Number Pack Size List Price* Quantity
42-1113-200 200 µg 511,00 Add

* CHF, excl. 7.7% VAT and shipping costs

Product Description

HSP90 is an abundantly and ubiquitously expressed heat shock protein. It is understood to exist in two principal forms alpha and beta, which share 85% sequence amino acid homology. The two isoforms of HSP90, are expressed in the cytosolic compartment. Despite the similarities, HSP90 alpha exists predominantly as a homodimer while HSP90 beta exists mainly as a monomer. From a functional perspective, HSP90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of a chaperone complex. Furthermore, HSP90 is highly conserved between species; having 60% and 78% amino acid similarity between mammalian and the corresponding yeast and Drosophila proteins, respectively. HSP90 is a highly conserved and essential stress protein that is expressed in all eukaryotic cells. Despite its label of being a heat-shock protein, HSP90 is one of the most highly expressed proteins in unstressed cells (12% of cytosolic protein). It carries out a number of housekeeping functions including controlling the activity, turnover, and trafficking of a variety of proteins. Most of the HSP90-regulated proteins that have been discovered to date are involved in cell signaling. The number of proteins now know to interact with HSP90 is about 1

Category Antibody
Supplier Abeomics
Application WB, IHC, IP, EL
Species Specificity Hu
Immunogen Recombinant human HSP60
Host Ms
Clone Number [LK1]
Genebank 3329
Isotype IgG1
Crossreactivity Hu, Ms, Rt, Bo, Dg, Ck, Drosophila, Gp , Mk, Pg, Rb, Sh
Clonality Mab
Working Dilution WB (1:20000), IHC (1:100), ICC/IF (1:100), IP (1:200); optimal dilutions for assays should be det...
Purity Protein G Purified
Conjugation Atto 594
Storage Conditions Store the antibody at 4°C
Product Line Research
Tech. Data Sheet View datasheet
Link To Supplier https://www.abeomics.com
Shipping Details Blue Ice
Material Safety Data Sheet Download PDF
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