Leptomycin B


Catalog Number Pack Size List Price* Quantity
HY-16909-1MG 1 mg 343,00 Add
HY-16909-5MG 5 mg 1'217,00 Add
HY-16909-10MG 10 mg 1'914,00 Add

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle[1].

Category Antibiotics
Supplier MedChem Express
Regulatory Status RUO
Research Field Cancer, Infection, Anti-infection,Membrane Transporter/Ion Channel
Format Solubility: DMSO : ≥ 100 mg/mL;H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
Grade Clinical information: No Development Reported
Purity 99.68%
Molecular Formula C33H48O6
Molecular Weight 540.73
CAS-Number 87081-35-4
Storage Conditions -20°C (Powder, stored under nitrogen)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Blue Ice
Material Safety Data Sheet Download PDF