Leptomycin B
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
HY-16909-1MG | 1 mg | 343,00 | Add | |
HY-16909-5MG | 5 mg | 1'217,00 | Add | |
HY-16909-10MG | 10 mg | 1'914,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle[1].
Category | Antibiotics |
Supplier | MedChem Express |
Regulatory Status | RUO |
Research Field | Cancer, Infection, Anti-infection,Membrane Transporter/Ion Channel |
Format | Solubility: DMSO : ≥ 100 mg/mL;H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) |
Grade | Clinical information: No Development Reported |
Purity | 99.68% |
Molecular Formula | C33H48O6 |
Molecular Weight | 540.73 |
CAS-Number | 87081-35-4 |
Storage Conditions | -20°C (Powder, stored under nitrogen) |
Tech. Data Sheet | View datasheet |
Link To Supplier | http://www.medchemexpress.com |
Shipping Details | Blue Ice |
Material Safety Data Sheet | Download PDF |