Dasminapant
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-125593-1MG | 1 mg | 837,00 | Add | |
| HY-125593-5MG | 5 mg | 2'484,00 | Add | |
| HY-125593-10MG | 10 mg | 4'131,00 | Add | |
| HY-125593-25MG | 25 mg | 8'247,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Dasminapant (APG-1387), a bivalent SMAC mimetic and an IAP antagonist, blocks the activity of IAPs family proteins (XIAP, cIAP-1, cIAP-2, and ML-IAP). Dasminapant induces degradation of cIAP-1 and XIAP proteins, as well as caspase-3 activation and PARP cleavage, which leads to apoptosis. Dasminapant can be used for the research of hepatocellular carcinoma, ovarian cancer, and nasopharyngeal carcinoma[1][2][3][4][5].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Apoptosis |
| Format | Solubility: DMSO : 50 mg/mL (ultrasonic) |
| Grade | Clinical information: Phase 2 |
| Purity | 99.36% |
| Molecular Formula | C60H72N10O10S2 |
| Molecular Weight | 1157.4 |
| CAS-Number | 1570231-89-8 |
| Storage Conditions | -20°C (Powder, stored under nitrogen) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Blue Ice |
| Material Safety Data Sheet | Download PDF |
