RWJ-56110
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-108556-1ST | Get quote | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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RWJ-56110 is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 inhibits the aggregation of human platelets induced by both SFLLRN-NH2 (IC50=0.16 μM) and thrombin (IC50=0.34 μM), quite selective relative to U46619 (HY-108566). RWJ-56110 inhibits angiogenesis and blocks the formation of new vessels in vivo. RWJ-56110 induces cell apoptosis[1][2].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cardiovascular Disease, Apoptosis,GPCR/G Protein |
| Format | Solubility: 10 mM in DMSO |
| Grade | Clinical information: No Development Reported |
| Molecular Formula | C41H43Cl2F2N7O3 |
| Molecular Weight | 790.73 |
| CAS-Number | 252889-88-6 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room temperature |
| Material Safety Data Sheet | Download PDF |
