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RWJ-56110


Catalog Number Pack Size List Price* Quantity
HY-108556-1MG 1 mg Inquire

* CHF, excl. 7.7% VAT and shipping costs


Product Description

RWJ-56110 is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 inhibits the aggregation of human platelets induced by both SFLLRN-NH2 (IC50=0.16 μM) and thrombin (IC50=0.34 μM), quite selective relative to U46619 (HY-108566). RWJ-56110 inhibits angiogenesis and blocks the formation of new vessels in vivo. RWJ-56110 induces cell apoptosis.

Category Biochemicals
Supplier MedChem Express
Application Neuroscience-Neurodegeneration
Regulatory Status RUO
Grade Clinical information: No Development Reported
Molecular Formula C41H43Cl2F2N7O3
Molecular Weight 790.73
CAS-Number [252889-88-6]
Storage Conditions Please store the product under the recommended conditions in the Certificate of Analysis.
Product Line Research
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Material Safety Data Sheet Download PDF
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