Eeyarestatin I


Catalog Number Pack Size List Price* Quantity
HY-110078-5MG 5 mg 241,00 Add
HY-110078-10MG 10 mg 393,00 Add
HY-110078-25MG 25 mg 545,00 Add
HY-110078-50MG 50 mg 862,00 Add
HY-110078-100MG 100 mg 1'255,00 Add
HY-110078-S-1ST Sample   Inquire

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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Eeyarestatin I, a potent endoplasmic reticulum-associated protein degradation (ERAD) inhibitor, is a potent protein translocation inhibitor. Eeyarestatin I inhibits Sec61 translocon. Eeyarestatin I targets the p97-associated deubiquitinating process (PAD) and inhibits atx3-dependent deubiquitination. Eeyarestatin I interferes at a step prior to proteasomal degradation. Eeyarestatin I induces cell death via the proapoptotic protein NOXA and has anticancer effects[1][2][3][4][5].

Category Biochemicals
Supplier MedChem Express
Regulatory Status RUO
Research Field Cancer, Apoptosis,Cell Cycle/DNA Damage
Format Solubility: DMSO : 25 mg/mL (ultrasonic)
Grade Clinical information: No Development Reported
Purity 98.96%
Molecular Formula C27H25Cl2N7O7
Molecular Weight 630.44
CAS-Number 412960-54-4
Storage Conditions -20°C (Powder, sealed storage, away from moisture)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Blue Ice
Material Safety Data Sheet Download PDF