Eeyarestatin I
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
HY-110078-5MG | 5 mg | 241,00 | Add | |
HY-110078-10MG | 10 mg | 393,00 | Add | |
HY-110078-25MG | 25 mg | 545,00 | Add | |
HY-110078-50MG | 50 mg | 862,00 | Add | |
HY-110078-100MG | 100 mg | 1'255,00 | Add | |
HY-110078-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Eeyarestatin I, a potent endoplasmic reticulum-associated protein degradation (ERAD) inhibitor, is a potent protein translocation inhibitor. Eeyarestatin I inhibits Sec61 translocon. Eeyarestatin I targets the p97-associated deubiquitinating process (PAD) and inhibits atx3-dependent deubiquitination. Eeyarestatin I interferes at a step prior to proteasomal degradation. Eeyarestatin I induces cell death via the proapoptotic protein NOXA and has anticancer effects[1][2][3][4][5].
Category | Biochemicals |
Supplier | MedChem Express |
Regulatory Status | RUO |
Research Field | Cancer, Apoptosis,Cell Cycle/DNA Damage |
Format | Solubility: DMSO : 25 mg/mL (ultrasonic) |
Grade | Clinical information: No Development Reported |
Purity | 98.96% |
Molecular Formula | C27H25Cl2N7O7 |
Molecular Weight | 630.44 |
CAS-Number | 412960-54-4 |
Storage Conditions | -20°C (Powder, sealed storage, away from moisture) |
Tech. Data Sheet | View datasheet |
Link To Supplier | http://www.medchemexpress.com |
Shipping Details | Blue Ice |
Material Safety Data Sheet | Download PDF |