DS-1205b free base
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DS-1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205b free base also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205b free base can inhibit cell migration in vitro and tumor growth in vivo.
|Format||Solubility: DMSO : 100 mg/mL (135.91 mM; Need ultrasonic)|
|Grade||Clinical information: No Development Reported|
|Storage Conditions||Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month|
|Tech. Data Sheet||View datasheet|
|Link To Supplier||http://www.medchemexpress.com|
|Material Safety Data Sheet||Download PDF|