DS-1205b (free base)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-114357A-5MG | 5 mg | 532,00 | Add | |
| HY-114357A-1ML | 10mM/1mL | 854,00 | Add | |
| HY-114357A-10MG | 10 mg | 862,00 | Add | |
| HY-114357A-25MG | 25 mg | 1'710,00 | Add | |
| HY-114357A-50MG | 50 mg | 2'737,00 | Add | |
| HY-114357A-100MG | 100 mg | 4'448,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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DS-1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205b free base also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205b free base can inhibit cell migration in vitro and tumor growth in vivo[1].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Neuronal Signaling,Protein Tyrosine Kinase/RTK |
| Format | Solubility: DMSO : 50 mg/mL (ultrasonic) |
| Grade | Clinical information: No Development Reported |
| Purity | 99.92% |
| Molecular Formula | C41H42FN5O7 |
| Molecular Weight | 735.8 |
| CAS-Number | 1855860-24-0 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
