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DS-1205b free base


Catalog Number Pack Size List Price* Promo Price* Quantity
HY-114357A-5MG 5 mg 656,00 557,60 Add
HY-114357A-10MG 10 mg 1'045,00 888,30 Add
HY-114357A-25MG 25 mg 2'144,00 1'822,40 Add
HY-114357A-50MG 50 mg 3'573,00 3'037,10 Add

* CHF, excl. 7.7% VAT and shipping costs


Product Description

DS-1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205b free base also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205b free base can inhibit cell migration in vitro and tumor growth in vivo.

Category Biochemicals
Supplier MedChem Express
Application Cancer-Kinase/protease
Regulatory Status RUO
Format Solubility: DMSO : 100 mg/mL (135.91 mM; Need ultrasonic)
Grade Clinical information: No Development Reported
Purity 99.92%
Molecular Formula C41H42FN5O7
Molecular Weight 735.8
CAS-Number [1855860-24-0]
Storage Conditions Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Product Line Research
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Material Safety Data Sheet Download PDF
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