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Catalog Number Pack Size List Price* Quantity
HY-124761-5MG 5 mg Inquire
HY-124761-10MG 10 mg Inquire

* CHF, excl. 7.7% VAT and shipping costs

Product Description

Poloppin is a potent, cell penetrant inhibitor of the mitotic Polo-like kinase (PLK) (IC50=26.9 μM) and prevents the protein-protein interaction via the Polo-box domain (PBD) (Kd= 29.5 μM). Poloppin selectively kills cells expressing mutant KRAS, enhancing death in mitosis. Poloppin is used for the study of KRAS-mutant cancers as single agents, or in combination with c-MET inhibitors.

Category Biochemicals
Supplier MedChem Express
Application COVID-19-anti-virus
Regulatory Status RUO
Grade Clinical information: No Development Reported
Molecular Formula C20H15BrF3NO2
Molecular Weight 438.24
CAS-Number [683808-78-8]
Storage Conditions Please store the product under the recommended conditions in the Certificate of Analysis.
Product Line Research
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Material Safety Data Sheet Download PDF
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