Logo Lucerna-Chem
+41 41 420 9636

Regulatory Status

Article Status


Poloppin


Catalog Number Pack Size List Price* Quantity
HY-124761-5MG 5 mg Inquire
HY-124761-10MG 10 mg Inquire

* CHF, excl. 7.7% VAT and shipping costs


Product Description

Poloppin is a potent, cell penetrant inhibitor of the mitotic Polo-like kinase (PLK) (IC50=26.9 μM) and prevents the protein-protein interaction via the Polo-box domain (PBD) (Kd= 29.5 μM). Poloppin selectively kills cells expressing mutant KRAS, enhancing death in mitosis. Poloppin is used for the study of KRAS-mutant cancers as single agents, or in combination with c-MET inhibitors.

Category Biochemicals
Supplier MedChem Express
Application COVID-19-anti-virus
Regulatory Status RUO
Grade Clinical information: No Development Reported
Molecular Formula C20H15BrF3NO2
Molecular Weight 438.24
CAS-Number [683808-78-8]
Storage Conditions Please store the product under the recommended conditions in the Certificate of Analysis.
Product Line Research
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Material Safety Data Sheet Download PDF
Call us

Customer Support
T +41 41 420 96 36
F +41 41 420 96 56
info@lucerna-chem.ch

Business Hours
From Monday through Friday
08:00 – 12:00
13:00 – 17:00

Ask us

Technical Support
tech@lucerna-chem.ch

Business Development
business.dev@lucerna-chem.ch

Postal address
Lucerna-Chem AG
Abendweg 18
CH-6006 Luzern

Newsletter













If you have already subscribed to our newsletter and would like to update your details or cancel it, please click here.


© Copyright 2021 Lucerna-Chem AG, Switzerland