FK706


Catalog Number Pack Size List Price* Quantity
HY-19269-5MG 5 mg 608,00 Add
HY-19269-10MG 10 mg 964,00 Add
HY-19269-25MG 25 mg 1'914,00 Add
HY-19269-50MG 50 mg 3'053,00 Add
HY-19269-100MG 100 mg 4'891,00 Add

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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FK706 is a potent, slow-binding and competitive inhibitor of human neutrophil elastase with an IC50 of 83 nM and a Ki of 4.2 nM. FK706 also inhibits mouse neutrophil elastase and porcine pancreatic elastase with IC50s of 22 nM and 100 nM, respectively, and has no inhibitory activity against other serine proteinases such as human pancreatic trypsin, human pancreatic α-chymotrypsin and human leukocyte cathepsin G. FK706 has anti-inflammatory effect[1][2].

Category Biochemicals
Supplier MedChem Express
Regulatory Status RUO
Research Field Inflammation/Immunology, Metabolic Enzyme/Protease
Format Solubility: DMSO : 115 mg/mL (ultrasonic);H2O : ≥ 100 mg/mL
Grade Clinical information: No Development Reported
Purity 99.16%
Molecular Formula C26H32F3N4NaO7
Molecular Weight 592.54
CAS-Number 144055-55-0
Storage Conditions 4°C (Powder, sealed storage, away from moisture)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room Temperature
Material Safety Data Sheet Download PDF