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FK706


Catalog Number Pack Size List Price* Promo Price* Quantity
HY-19269-5MG 5 mg 597,00 507,50 Add
HY-19269-10MG 10 mg 935,00 794,80 Add
HY-19269-25MG 25 mg 1'980,00 1'683,00 Add

* CHF, excl. 7.7% VAT and shipping costs


Product Description

FK706 is a potent, slow-binding and competitive inhibitor of human neutrophil elastase with an IC50 of 83 nM and a Ki of 4.2 nM. FK706 also inhibits mouse neutrophil elastase and porcine pancreatic elastase with IC50s of 22 nM and 100 nM, respectively, and has no inhibitory activity against other serine proteinases such as human pancreatic trypsin, human pancreatic α-chymotrypsin and human leukocyte cathepsin G. FK706 has anti-inflammatory effect.

Category Biochemicals
Supplier MedChem Express
Application COVID-19-immunoregulation
Regulatory Status RUO
Format Solubility: DMSO : 115 mg/mL (194.08 mM; Need ultrasonic)
Grade Clinical information: No Development Reported
Molecular Formula C26H32F3N4NaO7
Molecular Weight 592.54
CAS-Number [144055-55-0]
Storage Conditions 4°C, protect from light; In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Product Line Research
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Material Safety Data Sheet Download PDF
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