FK706
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
HY-19269-5MG | 5 mg | 608,00 | Add | |
HY-19269-10MG | 10 mg | 964,00 | Add | |
HY-19269-25MG | 25 mg | 1'914,00 | Add | |
HY-19269-50MG | 50 mg | 3'053,00 | Add | |
HY-19269-100MG | 100 mg | 4'891,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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FK706 is a potent, slow-binding and competitive inhibitor of human neutrophil elastase with an IC50 of 83 nM and a Ki of 4.2 nM. FK706 also inhibits mouse neutrophil elastase and porcine pancreatic elastase with IC50s of 22 nM and 100 nM, respectively, and has no inhibitory activity against other serine proteinases such as human pancreatic trypsin, human pancreatic α-chymotrypsin and human leukocyte cathepsin G. FK706 has anti-inflammatory effect[1][2].
Category | Biochemicals |
Supplier | MedChem Express |
Regulatory Status | RUO |
Research Field | Inflammation/Immunology, Metabolic Enzyme/Protease |
Format | Solubility: DMSO : 115 mg/mL (ultrasonic);H2O : ≥ 100 mg/mL |
Grade | Clinical information: No Development Reported |
Purity | 99.16% |
Molecular Formula | C26H32F3N4NaO7 |
Molecular Weight | 592.54 |
CAS-Number | 144055-55-0 |
Storage Conditions | 4°C (Powder, sealed storage, away from moisture) |
Tech. Data Sheet | View datasheet |
Link To Supplier | http://www.medchemexpress.com |
Shipping Details | Room Temperature |
Material Safety Data Sheet | Download PDF |