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Tat-NR2B9c


Catalog Number Pack Size List Price* Quantity
HY-P0117-5MG 5 mg Inquire
HY-P0117-25MG 25 mg Inquire
HY-P0117-10MMO 10 mM * 1 mL Inquire
HY-P0117-10MG 10 mg Inquire
HY-P0117-1MG 1 mg Inquire

* CHF, excl. 7.7% VAT and shipping costs


Product Description

Tat-NR2Bct; NA-1
Tat-NR2B9c (Tat-NR2Bct; NA-1) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy.

Category Biochemicals
Supplier MedChem Express
Application Neuroscience-Neurodegeneration
Regulatory Status RUO
Format Solubility: H2O : ≥ 50 mg/mL (19.85 mM)
Grade Clinical information: Phase 3
Molecular Formula C105H188N42O30
Molecular Weight 2518.88
CAS-Number [500992-11-0]
Storage Conditions Powder -80°C 2 years, -20°C 1 year; In solvent -80°C 6 months, -20°C 1 month
Product Line Research
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Material Safety Data Sheet Download PDF
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