Tat-NR2B9c
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-P0117-1MG | 1 mg | 120,00 | Add | |
| HY-P0117-5MG | 5 mg | 288,00 | Add | |
| HY-P0117-10MG | 10 mg | 440,00 | Add | |
| HY-P0117-25MG | 25 mg | 849,00 | Add | |
| HY-P0117-10MMO | 10mM/1mL | 939,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Tat-NR2B9c (Tat-NR2Bct; NA-1) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy[1][2][5].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Neurological Disease, Immunology/Inflammation,Membrane Transporter/Ion Channel,Neuronal Signaling |
| Format | Solubility: H2O : 100 mg/mL (ultrasonic) |
| Grade | Clinical information: No Development Reported |
| Purity | 99.97% |
| Molecular Formula | C105H188N42O30 |
| Molecular Weight | 2518.88 |
| CAS-Number | 500992-11-0 |
| Storage Conditions | -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Blue Ice |
| Material Safety Data Sheet | Download PDF |
