2′-Deoxy-2′-fluoroadenosine


Catalog Number Pack Size List Price* Quantity
HY-W039442-100MG 100 mg 46,00 Add

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Product Description

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2′-Deoxy-2′-fluoroadenosine can be used for the synthesis of 2′-Deoxy-2′-fluoro-modified oligonucleotides hybridized with RNA. 2′-Deoxy-2′-fluoroadenosine can be cleaved efficiently by E. coli purine nucleoside phosphorylase (PNP) to the toxic agent 2-fluoroadenine (FAde). 2′-Deoxy-2′-fluoroadenosine shows excellent in vivo activity against tumors expressing E. coli PNP[1].

Category Oligonucleotide
Supplier MedChem Express
Regulatory Status RUO
Research Field Cancer, Cell Cycle/DNA Damage
Format Solubility: DMSO : 50 mg/mL (ultrasonic)
Grade Clinical information: No Development Reported
Purity 99%
Molecular Formula C10H12FN5O3
Molecular Weight 269.23
CAS-Number 64183-27-3
Storage Conditions 4°C (Powder, stored under nitrogen)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room Temperature
Material Safety Data Sheet Download PDF